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What is synovitis of the knee joint?
Synovitis is inflammation of the synovial membrane lining the knee joint from the inside. During inflammation, the membrane produces excess fluid (effusion), leading to swelling, pain, and limited mobility.
Synovitis is not an independent disease, but a manifestation of an intra-articular problem: osteoarthritis, meniscus injury, trauma, autoimmune process. Therefore, treatment should target the cause, not just the symptom.
Causes of synovitis:
- Osteoarthritis — chronic inflammation due to cartilage destruction (most common cause)
- Meniscus Tear — fragments irritate the synovial membrane
- Trauma — contusion, sprain, ligament tear
- Gout and chondrocalcinosis — crystalline arthropathies
- Rheumatoid Arthritis — autoimmune inflammation
- Infection — septic synovitis (requires urgent treatment)
Facts about synovitis
- ICD-10: M65.9
- Most common cause: knee osteoarthritis
- Problem with punctures: fluid returns in days-weeks
- Problem with steroids: cartilage atrophy with repeated injections
- Key: elimination of the cause, not the symptom
Symptoms of synovitis
Typical symptoms
- Knee swelling (patellar ballotment)
- Pain with movement and at rest
- Sensation of heaviness and distension
- Local temperature increase
- Limited flexion/extension
- Morning stiffness
Forms of synovitis
- Acute — pronounced symptoms, rapid swelling
- Chronic — moderate effusion, exacerbations and remissions
- Recurrent — recurs after punctures and treatment
- Proliferative — thickening of the synovial membrane
Vicious cycle of synovitis
- Osteoarthritis → inflammation → effusion
- Puncture → temporary relief → recurrence
- Steroids → inflammation suppression → cartilage destruction
- MIBRAR® eliminates the cause and breaks the cycle
How MIBRAR® treats synovitis
Identifying the cause
MRI and ultrasound of the knee joint identify the cause of synovitis — osteoarthritis, meniscus tear, loose bodies, synovial membrane thickening. The treatment plan targets elimination of the cause.
Obtaining concentrates
From blood — CGF with potent anti-inflammatory cytokines (IL-1Ra, IL-10). From adipose tissue — Lipogems® with stem cells for regeneration of damaged tissues.
Injection into the joint
Under Sono Control Arm™ guidance, concentrates are injected into the joint cavity. Anti-inflammatory factors normalize synovial membrane function, stem cells restore damaged cartilage and menisci — the cause of inflammation.
Eliminating the cause
MIBRAR® acts on two levels: rapidly reduces inflammation (days) and eliminates its cause — regenerates cartilage, restores meniscus (weeks-months). Result — resolution of effusion without recurrence.
Treatment Results for the Knee Joint
Follow-up MRI demonstrates elimination of inflammation and restoration of knee joint structures after MIBRAR® — without steroids or punctures.
MIBRAR Case: Male, 49 years
Diagnosis: Grade IV gonarthrosis with chronic synovitis, subchondral edema, and osteonecrosis of the medial condyle. MRI (image 3) — pronounced bone marrow edema and reactive inflammation.
Result after 18 months (image 4): complete disappearance of subchondral edema, elimination of synovial membrane inflammation. MIBRAR® does not merely suppress inflammation — it eliminates its cause.
View case study →
MIBRAR Case: Male, 56 years
Sagittal MRI (image 5): meniscus tear with reactive synovitis — fluid in the joint cavity, inflammation of the synovial membrane. Green oval — zone of maximum pathology.
After 4 weeks (image 6): meniscus regeneration, disappearance of reactive effusion. MIBRAR® eliminated the root cause of synovitis (meniscus damage), not just its symptoms.
View case study →MIBRAR® Method Advantages
95% of interventions covered
MIBRAR® covers up to 95% of all spinal neurosurgery and orthopedic operations.
No anesthesia or incisions
Outpatient treatment via 0.3-1.5 mm puncture. No general anesthesia or hospitalization.
No age restrictions
Regeneration at any age. Safe for chronic conditions and anesthesia intolerance.
Rapid improvement
Concentrates have analgesic and anti-inflammatory properties. Relief within days.
Multiple zones at once
Simultaneous treatment of multiple discs or joints in one procedure.
Home the same day
No crutches, braces or rehabilitation needed. MRI follow-up at 8-16 weeks.
MIBRAR® Technology
Cyber Navi Hand™
Intraoperative robotic navigation system. Provides precise access to deep structures with 1 mm and 1 degree accuracy.
Sono Control Arm™
Device for intervention under sonographic control. Eliminates open surgeries with real-time visual monitoring.