What is carpal tunnel syndrome?

Carpal tunnel syndrome (CTS) is a compressive neuropathy of the median nerve in the area of the carpal (wrist) tunnel. The tunnel is formed by the carpal bones and the transverse carpal ligament (retinaculum flexorum). Nerve compression occurs due to thickening of the ligament or swelling of the tunnel contents.

CTS is the most common compressive neuropathy, affecting 3-6% of the adult population. Women are affected more often (ratio 3:1). Bilateral involvement occurs in 50-60% of patients.

Causes:

  • Prolonged computer work (typing, mouse use)
  • Manual labor with repetitive movements
  • Pregnancy and hormonal changes
  • Diabetes mellitus, hypothyroidism
  • Rheumatoid Arthritis
  • History of wrist injuries

Severity grades:

  • Mild — intermittent numbness, especially at night
  • Moderate — constant numbness, reduced sensation, pain
  • Severe — thenar muscle atrophy, loss of grip strength, permanent sensory loss

Facts about CTS

  • ICD-10: G56.0
  • Prevalence: 3-6% adults
  • Gender: women 3 times more often
  • Bilateral: 50-60% cases
  • Surgeries: 500 000+/year in USA
  • Recurrence after surgery: 3-25%

Symptoms of carpal tunnel syndrome

Early signs

  • Numbness and tingling in fingers I-III at night
  • Need to "shake out" the hand for relief
  • Sensation of finger swelling in the mornings
  • Tingling during computer work

Progression

  • Constant finger numbness
  • Pain in hand and wrist
  • Reduced fingertip sensation
  • Clumsiness (dropping objects)
  • Thumb weakness

Severe Stage

  • Thenar muscle atrophy (at the base of the thumb)
  • Loss of pinch and grip strength
  • Inability to button a shirt
  • Loss of tactile sensation
  • Chronic pain

Surgery vs MIBRAR®

Criterion Surgical Decompression Corticosteroid Injections MIBRAR®
Principle Transverse carpal ligament release Reducing swelling with medications Nerve regeneration + biological decompression
Anesthesia Local / regional None No anesthesia
Ligament Preservation ❌ Ligament permanently severed ✅ Preserved ✅ Preserved — decompression without incision
Grip Strength Reduced for 3-6 months No change No reduction
Nerve Regeneration ❌ Decompression only ❌ None ✅ Stem cells restore the nerve
Both Hands at Once ❌ One at a time Possible ✅ Yes

How MIBRAR® treats Carpal Tunnel Syndrome

01

Ultrasound Diagnosis

Sono Control Arm™ visualizes the median nerve, measures its cross-sectional area (>10 mm² = compression), and assesses the condition of tendons and the carpal tunnel ligament.

02

Biomaterial Preparation

CGF — anti-inflammatory factors and neurotrophic growth factors (NGF, BDNF). Lipogems® — stem cells with neuroregenerative potential.

03

Targeted Injection

Under ultrasound guidance, concentrates are injected into the carpal tunnel — around the median nerve, into the thickened transverse carpal ligament, and into the area of maximum compression. Hydrodissection technique releases the nerve.

04

Neuroregeneration

Stem cells restore the myelin sheath of the damaged nerve, reduce ligament fibrosis, and relieve swelling. Result — elimination of compression and restoration of nerve conduction.

Why MIBRAR® is effective for CTS

Surgery for CTS severs the ligament — this relieves pressure but does not restore the damaged nerve. MIBRAR® addresses both problems: ultrasound-guided hydrodissection frees the nerve without incision, while stem cells trigger neuroregeneration — restoration of the myelin sheath and axons. Neurotrophic factors (NGF, BDNF) from CGF stimulate nerve fiber growth. Result — not only decompression but also restoration of nerve conduction.

MIBRAR® Method Advantages

95% of interventions covered

MIBRAR® covers up to 95% of all spinal neurosurgery and orthopedic operations.

No anesthesia or incisions

Outpatient treatment via 0.3-1.5 mm puncture. No general anesthesia or hospitalization.

No age restrictions

Regeneration at any age. Safe for chronic conditions and anesthesia intolerance.

Rapid improvement

Concentrates have analgesic and anti-inflammatory properties. Relief within days.

Multiple zones at once

Simultaneous treatment of multiple discs or joints in one procedure.

Home the same day

No crutches, braces or rehabilitation needed. MRI follow-up at 8-16 weeks.

MIBRAR® Technology

Cyber Navi Hand™ — MIBRAR® navigation system

Cyber Navi Hand™

Intraoperative robotic navigation system. Provides precise access to deep structures with 1 mm and 1 degree accuracy.

Sono Control Arm™ — MIBRAR® ultrasound control

Sono Control Arm™

Device for intervention under sonographic control. Eliminates open surgeries with real-time visual monitoring.

Video about the MIBRAR® Method

Frequently Asked Questions about CTS Treatment

When will numbness resolve after MIBRAR®?
Reduction in pain and nighttime numbness — within the first days. Full sensory recovery — from 2 weeks to 3 months depending on the degree of nerve damage. The earlier treatment begins, the faster the recovery.
Can both hands be treated simultaneously?
Yes. With bilateral Carpal Tunnel Syndrome (50-60% of cases), MIBRAR® treats both hands in a single procedure. With surgery, one hand is treated at a time with intervals of months between procedures.
Why preserve the transverse ligament?
The transverse ligament is a stabilizing structure of the wrist. Dividing it reduces grip strength for 3-6 months. MIBRAR® eliminates nerve compression biologically (hydrodissection + antifibrotic effect) without cutting the ligament.
Will MIBRAR® help with thenar muscle atrophy?
With early-stage atrophy, yes—nerve regeneration restores muscle innervation. With severe, long-standing atrophy, recovery may be incomplete. This is why it is important to begin treatment as soon as possible—before significant muscle loss occurs.

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