What is Dupuytren's Contracture?

Dupuytren's Contracture is a chronic condition in which the palmar aponeurosis thickens and scars, forming dense cords that gradually pull the fingers into a flexed position. It most commonly affects the ring finger and little finger.

The condition occurs in 4-6% of the population, predominantly in men over 50 years of age of European descent. The main problem with surgical treatment is the high recurrence rate (up to 60-70%) after fasciectomy.

Stages (Tubiana classification):

  • N — nodules without contracture
  • I — total contracture 0-45°
  • II — contracture 45-90°
  • III — contracture 90-135°
  • IV — contracture more than 135°

Symptoms:

  • Dense nodules and cords on the palm
  • Gradual finger flexion
  • Inability to fully extend the finger
  • Difficulty with handshaking and grasping objects
  • Inability to place the hand flat on the table (Hueston test)

Facts about Dupuytren

  • ICD-10: M72.0
  • Prevalence: 4-6% of population
  • Gender: men 6-10 times more often
  • Age: over 50 years
  • Recurrence after surgery: 60-70%

How MIBRAR® treats Dupuytren's Contracture

01

Ultrasound assessment

Sono Control Arm™ visualizes nodules, cords, and their position relative to finger nerves and vessels. The degree of contracture is assessed.

02

Obtaining concentrates

CGF — antifibrotic factors and matrix metalloproteinases. Lipogems® — stem cells with potent antifibrotic effects that suppress myofibroblasts.

03

Injection into fibrotic area

Under ultrasound guidance, concentrates are injected directly into nodules and cords — precisely into the fibrotic zone, avoiding nerves and vessels.

04

Tissue remodeling

Stem cells suppress myofibroblasts and trigger scar tissue remodeling. The cords soften, and elasticity is restored. Fingers gradually straighten.

MIBRAR® Method Advantages

95% of interventions covered

MIBRAR® covers up to 95% of all spinal neurosurgery and orthopedic operations.

No anesthesia or incisions

Outpatient treatment via 0.3-1.5 mm puncture. No general anesthesia or hospitalization.

No age restrictions

Regeneration at any age. Safe for chronic conditions and anesthesia intolerance.

Rapid improvement

Concentrates have analgesic and anti-inflammatory properties. Relief within days.

Multiple zones at once

Simultaneous treatment of multiple discs or joints in one procedure.

Home the same day

No crutches, braces or rehabilitation needed. MRI follow-up at 8-16 weeks.

MIBRAR® Technology

Cyber Navi Hand™ — MIBRAR® navigation system

Cyber Navi Hand™

Intraoperative robotic navigation system. Provides precise access to deep structures with 1 mm and 1 degree accuracy.

Sono Control Arm™ — MIBRAR® ultrasound control

Sono Control Arm™

Device for intervention under sonographic control. Eliminates open surgeries with real-time visual monitoring.

Video about the MIBRAR® Method

Frequently Asked Questions About Dupuytren's Contracture Treatment

Why is MIBRAR® better than surgery for Dupuytren's?
The main problem with surgery is recurrence up to 60-70%. Surgery removes the scar but does not eliminate the cause of fibrosis. MIBRAR® works at the cellular level—it suppresses myofibroblasts responsible for scar tissue formation. This significantly reduces the risk of recurrence. No general anesthesia, no incisions, no rehabilitation.
At what stage is it best to start treatment?
Optimal timing is at stage N-II (nodules and early contracture). The earlier treatment begins, the better the result. At advanced stages (III-IV), MIBRAR® can soften the cords and reduce contracture, but complete straightening is less likely.
How does MIBRAR® differ from collagenase injections (Xiapex)?
Collagenase (Xiapex) chemically dissolves the cord but does not eliminate the cause of fibrosis—recurrence is 50%+. Additionally, the drug has been withdrawn from the market in Europe. MIBRAR® suppresses myofibroblasts and remodels tissue biologically, with a lower recurrence risk and without side effects.

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